Markow Lab

Tom Watts

Senior Research Specialist

Tom received his bachelor's degree from the University of Connecticut in Pathobiology and an M.S. degree from the University of Montana in Environmental Studies. He has twenty years research experience and three years experience as a tribal college instructor of natural resources, human anatomy and physiology, and chemistry. His current research interests include genomics and adaptation of drosophilids to harsh environments.

Contact Information: twatts@u.arizona.edu

Publications

Schaeffer, S. W., Bhutkar, A., McAllister, B. F., et al. (Watts, T. co-author) 2008 (in press). Polytene Chromosomal Maps of 11 Drosophila species: The order of genomic scaffolds inferred from genetic and physical maps. Genetics.

Pfeiler, E., Watts, T., Pugh, J., van der Heiden, A. 2008 (in press). Speciation and demographic history of the Cortez bonefish, Albula sp. A (Albuliformes: Albulidae), in the Gulf of California inferred from mitochondrial DNA. Journal of Fish Biology

Matzkin, L., Watts, T.D. and Markow, T.A. 2007. Desiccation Resistance in Four Drosophila Species: Sex and Population Effects. Fly, 1:5, 268-273.

Drosophila 12 Genomes Consortium 2007 (Watts, T., Co-author). Evolution of genes and genomes on the Drosophila phylogeny. Nature 450:203-216.

Elser, J. Watts, T. Bitler, B. and Markow, T.A. 2006. Ontogenetic coupling of growth rate with RNA and P contents in five species of Drosophila. Functional Ecology, in press

Matzkin, L.M., Watts, T.D., Bitler, B.G., Machado, C.A. and Markow, T.A. 2006. Functional genomics of cactus host shifts in Drosophila mojavensis. Molecular Ecology. doi: 10.1111/j.1365-294X.2006.03102.x

Watts, T., Woods, H.A., Hargand, S., Elser, J.J. and Markow T.A. 2006. Biological stoichiometry of growth in Drosophila melanogaster. Journal of Insect Physiology, 52(2): 187-193.

Carsten, L. Watts, T. and Markow, T.A. 2005. Gene expression changes following dietary shifts in Drososphila melanogaster. Molecular Ecology.

Kyle, M., Watts , T., Schade, J. and J.J. Elser 2003 A microfluorometric method for quantifying RNA and DNA in terrestrial insects. Journal of Insect Science 3:1-12.

Elser, J.J., Acharya, K., Kyle, M., Cotner, J., Makino, W., Markow, T., Watts , T., Hobbie, S., Fagan, W., Schade, J., Hood, J., and Sterner, R.W. 2003 . Growth rate--stoichiometry couplings in diverse biota. Ecology Letters 6:936-943.

Markow, T.A., Coppola, A., Watts, T. 2001. How Drosophila males make eggs: it's elemental. Proceedings of the Royal Society, Series B. 268: 1527-1532.

Bianchi, A, Evans, L, Nordlund, A.C, Watts, T.D, Witters, L.A. 1992. Acetyl-CoA carboxylase in Reuber hepatoma cells: variation in enzyme activity, insulin regulation, and cellular lipid content. J Cell Biochem 48(1): 86-97.

Witters, L.A, and Watts, T.D. 1990. Yeast acetyl-CoA carboxylase: in vitro phosphorylation by mammalian and yeast protein kinases. Biochem Biophys Res Commun 169(2): 369-76.

Bianchi, A, Evans, J.L, Iverson, A.J, Nordlund, A.C, Watts, T.D, Witters, L.A. 1990. Identification of an isozymic form of acetyl-CoA carboxylase. J Biol Chem 265(3): 1502-9.

Witters, L.A, Watts, T.D, Gould, G.W, Lienhard, G.E, Gibbs, E.M. 1988. Regulation of protein phosphorylation by insulin and an insulinomimetic oligosaccharide in 3T3-L1 adipocytes and Fao hepatoma cells. Biochem Biophys Res Commun 153(3): 992-8.

Witters, L.A, Watts,T.D, Daniels,D.L, Evans,J.L. 1988. Insulin stimulates the dephosphorylation and activation of acetyl-CoA carboxylase. Proc Natl Acad Sci USA. 85(15): 5473-7.

Witters, L.A and Watts,T.D. 1988. An autocrine factor from Reuber hepatoma cells that stimulates DNA synthesis and acetyl-CoA carboxylase: Characterization of biologic activity and evidence for a glycan structure. J Biol Chem 263(7): 8027-36.

Grabel, L.B and Watts, T.D. 1987. The role of extracellular matrix in the migration and differentiation of parietal endoderm from teratocarcinoma embryoid bodies. J Cell Biol 105(1):441-8.

Gallicchio, V.S, Watts, T.D, DellaPuca, R. 1987. Synergistic action of recombinant-derived murine interleukin-1 on the augmentation of colony stimulating activity on murine granulocyte-macrophage hematopoietic stem cells in vitro. Exp Cell Biol 55(2): 83-92.

Gallicchio, V.S, Casale, G.P, Watts,T.D. 1987. Inhibition of human bone marrow-derived stem cell colony formation (CFU-E, BFU-E, and CFU-GM) following in vitro exposure to organophosphates. Exp Hematol. 15(11): 1099-102.

Gallicchio, V.S, Casale, G.P, Bartholomew, P.M, Watts, T.D. 1987. Altered colony-forming activities of bone marrow hematopoietic stem cells in mice following short-term in vivo exposure to parathion. Int J Cell Cloning. 5(3): 231-41.

Gallicchio, V.S, Gamba-Vitalo, C, Watts, T.D. 1986. In vivo and in vitro modulation of megakaryocytopoiesis and stromal colony formation by lithium. Chen MG J Lab Clin Med. 108(3): 199-205.

Gallicchio, V.S, Chen, M.G, Watts, T.D. 1985. Regeneration of murine megakaryocytopoiesis and the hematopoietic inductive microenvironment after sublethal whole body irradiation by treatment with an anabolic steroid. Acta-Hemaetol. 73(2): 80-5.

Gallicchio, V.S, Chen, M.G, Watts, T.D. 1985. Lithium stimulated recovery of granulopoiesis after sublethal irradiation is not mediated via increased levels of colony stimulating factor (CSF). Int J Radiat Biol Relat Stud Phys Chem Med 7(5):581-90.

Gallicchio,V.S,Chen, M.G, Watts, T.D. 1984. Ability of lithium to accelerate the recovery of granulopoiesis after subacute radiation injury. Acta Radiol Oncol 23(5): 361-6.

Gallicchio, V.S, Chen,M.G, Watts, T.D. 1984. The enhancement of committed hematopoietic stem cell colony formation by nandrolone decanoate after sublethal whole body irradiation. Int J Cell Cloning 2(6): 383-93.

Gallicchio, V.S, Chen, M.G, Watts, T.D. 1984. Specificity of lithium (Li+) to enhance the production of colony stimulating factor (GM-CSF) from mitogen-stimulated lymphocytes in vitro. Cell Immunol 85(1): 58-66.

Gallicchio, V.S, Chen, M.G, Gamba-Vitalo, C, Watts, T.D. 1983. The influence of choline chloride on murine hematopoiesis in vivo and in vitro. Int J Cell Cloning 1(6): 451-63.

Gallicchio, V.S, Chen, M.G, Gamba-Vitalo,C, Watts, T.D. 1983. Lithium stimulates the recovery of granulopoiesis following acute radiation injury. Exp. Hematol 11(6): 553-63.

Gamba-Vitalo, C, Gallicchio, V.S, Watts, T.D, Chen, M.G. 1983. Lithium stimulated in vitro megakaryocytopoiesis. Exp Hematol 11(5): 382-8.

Poster Presentations:

Coppola, A.M, Watts, T.D, Markow, T.A. An examination of seminal phosphorus donations and female incorporation of these donations in two species of Drosophila. University of Arizona, Center For Insect Science Poster Hexapodium. 1999 Tucson, AZ.

Watts, T.D, Souslova, L, Markow, T.A. Examination of the relative desiccation resistance of Drosophila species endemic to the Sonoran desert. University of Arizona, Center For Insect Science Poster Hexapodium. 1999 Tucson, AZ.