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News

Ancient Biological Clockwork Revealed Using ‘Secret Sauce’

A new paper released in the prestigious journal Science explains how the labs of LiWang and his colleagues — Professor Carrie Partch in the Department of Chemistry and Biochemistry at UC Santa Cruz and Professor Susan Golden in the Division of Biological Sciences at UC San Diego — captured assemblies of the proteins that direct cyanobacterial circadian rhythms, or biological clocks, in large complexes and made spectroscopic “snapshots” of their different formations using X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy.