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BI**194 / BGGN 280-285: Spring 2024 Course Descriptions

Disclaimer: Students may not receive credit for a second attempt of the same topic that was previously completed.

Course BIBC 194 A00 / BGGN 280 A00
Instructor Ernst, Andreas
Title Mechanistic Cell Biology
Description We will discuss recent publications from UCSD faculty who perform research in the field of ‘Mechanistic Cell Biology’. The goal for this course is to learn how to critically read and interpret primary literature, and to gain an overview of state-of-the art methods employed in current research at UCSD.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BIBC 194 B00
Instructor Saier, Milton
Title TBD
Description TBD
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BIBC 194 C00 / BGGN 280 C00
Instructor Amaro, Rommie
Title Computational Structural Biology
Description Computational Structural Biology is undergoing a revolution, thanks to increased experimental datasets, algorithmic advances, and continually evolving computer hardware. For example, AlphaFold made real the promise and use of artificial intelligence (AI) methods to enormous gain for the scientific community. In parallel, molecular, subcellular, and cell-scale simulations use, integrate, and extend experimental datasets providing novel hypotheses and views into regions of time and space that are otherwise inaccessible to experiment. This course will cover an overview of modern computational structural biology methods, through reading, discussing, and presenting primary literature.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BIBC 194 D00
Instructor Flagg, Matthew
Title Structure, Disease, Medicine
Description We'll use protein structure to understand human disease and commonly used therapeutics. Our central focus will be to visualize and characterize protein-drug interactions.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BICD 194 A00 / BGGN 281 A00
Instructor Desai, Arshad / Oegema, Karen
Title Cancer: Origins and Therapeutic Strategies
Description In this course, we will read primary scientific literature highlighting basic scientific findings and how they are leading to new therapeutic approaches in cancer. Students will read, present and discuss scientific papers and turn in a final written assignment analyzing an assigned pair of papers.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BICD 194 B00
Instructor Wilhelm, James
Title Unsolved Problems in Cell Biology
Description After a review of how to use biochemistry and genetics to answer questions in cell biology, students will work in groups on their own solutions to a set of unsolved cell biological problems and present their proposal to the class. Possible problems include: karyoklepty, suctorian biology, and photosymbiosis as well as others.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BIMM 194 A00 / BGGN 283 A00
Instructor Rivera Chavez, Fabian
Title Bacterial Virulence Factors and Pathogenesis in the Mammalian Host
Description This course provides an overview of the field of bacterial pathogenesis. The goal of the course is to learn about the molecular mechanisms of bacterial virulence factors and microbial interactions within mammalian hosts. Students will focus on reading, critically evaluating, and presenting primary research literature.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BIMM 194 B00 / BGGN 283 B00
Instructor Russell, Alistair
Title High-throughput genetics as applied to biological systems
Description In the modern era, sequencing and computational analysis has allowed for the simultaneous measurement of thousands of perturbations to cellular, or microbial, systems. Classical genetic approaches, with one gene and one phenotype, can now be expanded dramatically to understand how entire genomes encode complex behaviors. This class will cover the foundations of sequencing, caveats in data analysis, and new techniques in high-throughput genetics as applied to cellular or microbial systems. Students should have a solid foundation in molecular biology and ideally genetics before taking this class. Students will read and discuss primary literature as a means of understanding the state-of-the-art applications of these methods.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BIMM 194 D00 / BGGN 283 D00
Instructor Wildonger, Jill
Title CRISPR Technologies in Modern Biology
Description CRISPR has revolutionized gene editing and opened up new possibilities in research, disease treatment, food production, and disease detection, to name a few. We will discuss the emergence of gene editing technologies, and the expansion of approaches made possible by CRISPR-Cas9 and other CRISPR-based systems. Throughout the course, you will also acquire the skills to interpret, evaluate, and present primary literature.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BIPN 194 A00 / BGGN 284 A00
Instructor Glasgow, Stacey
Title Glia in health and disease
Description This is an advanced primary literature based seminar course that discusses current work on the role of glial cells in disease.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BISP 194 A00 / BGGN 285 A00
Instructor Chisholm, Andrew
Title Biology of Regeneration
Description Student-led discussion of primary research articles in modern regenerative biology in animal models.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Course BISP 194 B00 / BGGN 285 B00
Instructor Farley, Emma
Title Gene Regulation
Description We will read and discuss papers relating to gene regulation.
Prerequisites Please see the Biology Course Prerequisites page for most current prerequisite information.
Questions? Contact Student & Instructional Services (Pacific Hall 1128) through the Virtual Advising Center (VAC) or by phone at 858-534-0557