My laboratory studies how stochastic, genetic, and environmental variation is filtered through development and physiology to produce phenotypic variation and how evolutionary forces shape that process. We work primarily at the level of gene expression, taking advantage of technologies for visualizing gene expression dynamics at single-transcript resolution, among others. Current projects in the lab include probing the dynamics and robustness of the genetic networks underlying sex-determination and intestinal specification in nematodes and investigating how natural variation affects the dynamic properties of signaling and regulatory networks in yeasts.
Individual transcripts of xol-1 (yellow) and sdc-2 (red) in early C. elegans embryos. Blue spots are DAPI-stained nuclei.
Scott Rifkin received his PhD from Yale University and was a postdoctoral fellow at Harvard and an NIH postdoctoral fellow at MIT. He joined the faculty of UCSD in the summer of 2009.