David Kleinfeld
Research
The Kleinfeld laboratory takes engineering and physiological approaches to bridge phenomena at different levels in neuroscience, ranging from animal behavior to intracellular electrophysiology to multi-cellular electrical and optical recording. This provides an opportunity to discover principles that underlie computations within nervous systems. In addition, the laboratory develops instrumentation and algorithms that facilitate the study of physiology, with a current focus on optical imaging and automated histology. In broad terms, there are two ongoing themes that direct the flow of inquiry. The first relates to brain vasculature and lymphatic architectonics and flow dynamics. The second relates to active sensation at the level of sensorimotor loops within the brainstem and encompassing higher brain areas. These share common preparations, common measurement and analysis tools, and a critical overlap of scientific issues.
Biography
David Kleinfeld received his Ph.D. from UCSD in mid 1984, spent a decade on the research staff of Bell Laboratories, and then joined the faculty at UCSD in late 1995. He is a recipient of a David and Lucile Packard Foundation Interdisciplinary Science Award, a NIH Directors Pioneer Award, a NINDS Research Program Award, currently holds the Dr. George Feher Experimental Biophysics Endowed Chair, and is funded primarily through the NIH BRAIN initiative, where he leads the "Low&High" Team BRAIN Circuits Program. David is a fellow of the American Association for the Advancement of Science and a member of the American Academy of Arts and Sciences. He currently leads the Specialization on Computational Neuroscience through the Neurosciences Graduate Program.
